Loratidine and fexofenadine are obvious choices as first-line antihistamines when lack of sedation is important. Cetirizine is considered "low sedating" and would be appropriate as well. When the pharmacologic equivalent of a potentially toxic drug is introduced that has the same efficacy without toxicity, it is time to withdraw the drug. That time has come for terfenadine.
Mechanism of the cardiotoxic actions of terfenadine. JAMA Cardiac actions of antihistamines. Annu Rev Pharmacol Toxicol 36 Grapefruit juice alters terfenadine pharmacokinetics, resulting in prolongation of repolarization on the electrocardiogram.
Clin Pharmacol Ther 59 Pharmacies and prevention of potentially fatal drug interactions. Temporal decline in filling prescriptions for terfenadine closely in time with those for either ketoconazole or erythromycin.
Clin Pharmacol Ther 61 Citation s : 1 FDA proposes to withdraw Seldane approval. Peanut allergy. Clin Exp Allergy 25 October 17, Family Medicine. Salisbury, North Carolina. New York City, New York. Surgery, General. Fort Collins, Colorado. Psychiatry at the NC Coast.
North Carolina. TRIP on Terfenadine. Ongoing Trials on Terfenadine at Clinical Trials. Trial results on Terfenadine. Clinical Trials on Terfenadine at Google.
FDA on Terfenadine. CDC on Terfenadine. Books on Terfenadine. Terfenadine in the news. Be alerted to news on Terfenadine. News trends on Terfenadine. Blogs on Terfenadine. Definitions of Terfenadine. Patient resources on Terfenadine. Discussion groups on Terfenadine. Patient Handouts on Terfenadine. Directions to Hospitals Treating Terfenadine. Risk calculators and risk factors for Terfenadine. Symptoms of Terfenadine. Diagnostic studies for Terfenadine.
Treatment of Terfenadine. CME Programs on Terfenadine. Terfenadine en Espanol. Antihistamines prevent sneezing, runny nose, itching and watering of the eyes, and other allergic symptoms. Seldane is used to treat allergies, hives urticaria , and other allergic inflammatory conditions.
What is the meaning of terfenadine? Terfenadine is an antihistamine. Terfenadine is used to treat allergies, hives urticaria , and other allergic inflammatory conditions. Why was cisapride removed from the market? Cisapride has been voluntarily withdrawn because of the increased risk of cardiac arrhythmias in patients taking other medications or suffering from underlying conditions known to increase risk of cardiac arrhythmias.
When the antihistamine Seldane was first introduced? Introduced in , Seldane was the first prescription antihistamine to relieve symptoms of allergies like sneezing, itching and runny nose without causing drowsiness. But within a few years, serious problems were reported. What is cisapride used for? Cisapride has been used widely to treat gastric-emptying disorders, intestinal transit and other motility disorders in both dogs and cats.
It accelerates emptying the stomach and propulsion of food through the intestines by increasing peristalsis. Cisapride is used in cats to manage chronic constipation and megacolon.
What are antihistamine medications? Is cisapride available in the US? Cisapride is only available in the United States to special patients who are signed up by their doctors.
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